| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor B |
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| Ligand | BDBM50042225 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_34806 |
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| IC50 | 24±n/a nM |
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| Citation |  Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clément, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA A new series of imidazolones: highly specific and potent nonpeptide AT1 angiotensin II receptor antagonists. J Med Chem36:3371-80 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor B |
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| Name: | Type-1 angiotensin II receptor B |
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| Synonyms: | AGTRB_RAT | AT3 | Agtr1 | Agtr1b | Angiotensin II AT1B | Angiotensin II receptor (AT-1) type-1 | Angiotensin II type 1b (AT-1b) receptor | At1b | Type-1B angiotensin II receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40929.44 |
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| Organism: | RAT |
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| Description: | Angiotensin II AT1B 0 RAT::P29089 |
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| Residue: | 359 |
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| Sequence: | MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFR
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE
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| BDBM50042225 |
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| n/a |
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| Name | BDBM50042225 |
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| Synonyms: | 4'-(4-Oxo-2-pentyl-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid | CHEMBL114267 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H30N2O3 |
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| Mol. Mass. | 418.528 |
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| SMILES | CCCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:5| |
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| Structure | 
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