Reaction Details |
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Target | Thromboxane A2 receptor |
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Ligand | BDBM50047273 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_212937 |
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Kd | 1±n/a nM |
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Citation | Misra, RN; Brown, BR; Sher, PM; Patel, MM; Hall, SE; Han, WC; Barrish, JC; Kocy, O; Harris, DN; Goldenberg, HJ Interphenylene 7-oxabicyclo[2.2.1]heptane oxazoles. Highly potent, selective, and long-acting thromboxane A2 receptor antagonists. J Med Chem36:1401-17 (1993) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Thromboxane A2 receptor |
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Name: | Thromboxane A2 receptor |
Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
Type: | Enyzme |
Mol. Mass.: | 37445.28 |
Organism: | Homo sapiens (Human) |
Description: | P21731 |
Residue: | 343 |
Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
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BDBM50047273 |
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n/a |
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Name | BDBM50047273 |
Synonyms: | 2-{3-[2-(2-Carboxy-ethyl)-benzyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-oxazole-4-carboxylic acid 4-cyclohexyl-butyl ester | CHEMBL286978 |
Type | Small organic molecule |
Emp. Form. | C30H39NO6 |
Mol. Mass. | 509.6338 |
SMILES | OC(=O)CCc1ccccc1CC1C2CCC(O2)C1c1nc(co1)C(=O)OCCCCC1CCCCC1 |TLB:11:12:17:15.14,THB:19:18:17:15.14| |
Structure |
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