| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50051678 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_29636 (CHEMBL639743) |
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| Ki | >30000±n/a nM |
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| Citation |  Müller, CE; Geis, U; Grahner, B; Lanzner, W; Eger, K Chiral pyrrolo[2,3-d]pyrimidine and pyrimido[4,5-b]indole derivatives: structure-activity relationships of potent, highly stereoselective A1-adenosine receptor antagonists. J Med Chem39:2482-91 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
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| Type: | Protein |
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| Mol. Mass.: | 36704.13 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
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| BDBM50051678 |
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| n/a |
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| Name | BDBM50051678 |
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| Synonyms: | CHEMBL82038 | R-2'-phenyl-7'-[1-phenyl-(1R)-ethyl]spiro[cyclopentane-1,5'-(4',5',6',7'-tetrahydro-3'H-pyrrolo[2,3-d]pyrimidine)]-4',6'-dione |
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| Type | Small organic molecule |
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| Emp. Form. | C24H23N3O2 |
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| Mol. Mass. | 385.4583 |
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| SMILES | C[C@@H](N1C(=O)C2(CCCC2)c2c1nc([nH]c2=O)-c1ccccc1)c1ccccc1 |
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| Structure | 
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