| Reaction Details |
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 | Report a problem with these data |
| Target | Adenylate cyclase type 1 |
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| Ligand | BDBM50052124 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_31878 (CHEMBL645668) |
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| IC50 | 32±n/a nM |
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| Citation |  Robbins, JD; Boring, DL; Tang, WJ; Shank, R; Seamon, KB Forskolin carbamates: binding and activation studies with type I adenylyl cyclase. J Med Chem39:2745-52 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenylate cyclase type 1 |
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| Name: | Adenylate cyclase type 1 |
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| Synonyms: | ADCY1 | ADCY1_HUMAN | Adenylate cyclase | Brain adenylate cyclase 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 123469.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_31877 |
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| Residue: | 1119 |
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| Sequence: | MAGAPRGGGGGGGGAGEPGGAERAAGTSRRRGLRACDEEFACPELEALFRGYTLRLEQAA
TLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQLQ
QVGQLALLFSLTFALLCCPFALGGPARGSAGAAGGPATAEQGVWQLLLVTFVSYALLPVR
SLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFVGVNMYGVFVRILTERSQR
KAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHD
NVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGL
TQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWS
NDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGYGHERNSFLKTHNIETFFIVPSH
RRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALR
TASEKLRNRSSFSTNVVYTTPGTRVNRYISRLLEARQTELEMADLNFFTLKYKHVEREQK
YHQLQDEYFTSAVVLTLILAALFGLVYLLIFPQSVVVLLLLVFCICFLVACVLYLHITRV
QCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSKPNSSLVVLSSGGQRTALP
TLPCESTHHALLCCLVGTLPLAIFFRVSSLPKMILLSGLTTSYILVLELSGYTRTGGGAV
SGRSYEPIVAILLFSCALALHARQVDIRLRLDYLWAAQAEEEREDMEKVKLDNRRILFNL
LPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEI
IADFDELMEKDFYKDIEKIKTIGSTYMAAVGLAPTSGTKAKKSISSHLSTLADFAIEMFD
VLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQV
TEEVHRLLRRCPYHFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQIRSLGLDRKMCPFGRA
GLQGRRPPVCPMPGVSVRAGLPPHSPGQYLPSAAAGKEA
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| BDBM50052124 |
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| n/a |
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| Name | BDBM50052124 |
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| Synonyms: | Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-10,10b-dihydroxy-6-(2-methoxy-ethylcarbamoyloxy)-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyl-dodecahydro-benzo[f]chromen-5-yl ester | CHEMBL92229 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H41NO9 |
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| Mol. Mass. | 511.605 |
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| SMILES | COCCNC(=O)O[C@@H]1[C@H](OC(C)=O)[C@@]2(C)O[C@](C)(CC(=O)[C@]2(O)[C@@]2(C)[C@@H](O)CCC(C)(C)[C@H]12)C=C |
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| Structure | 
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