| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50508672 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1833777 (CHEMBL4333785) |
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| Ki | 14±n/a nM |
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| Citation |  Varano, F; Catarzi, D; Falsini, M; Dal Ben, D; Buccioni, M; Marucci, G; Volpini, R; Colotta, V Novel human adenosine receptor antagonists based on the 7-amino-thiazolo[5,4-d]pyrimidine scaffold. Structural investigations at the 2-, 5- and 7-positions to enhance affinity and tune selectivity. Bioorg Med Chem Lett29:563-569 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50508672 |
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| n/a |
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| Name | BDBM50508672 |
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| Synonyms: | CHEMBL4439172 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H10N4O2S |
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| Mol. Mass. | 298.32 |
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| SMILES | Cc1ccc(o1)-c1nc(N)c2nc(sc2n1)-c1ccco1 |
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| Structure | 
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