| Reaction Details |
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 | Report a problem with these data |
| Target | Aurora kinase B |
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| Ligand | BDBM50509368 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1838066 (CHEMBL4338199) |
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| IC50 | >10000±n/a nM |
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| Citation |  Hansen, KØ; Andersen, JH; Bayer, A; Pandey, SK; Lorentzen, M; Jørgensen, KB; Sydnes, MO; Guttormsen, Y; Baumann, M; Koch, U; Klebl, B; Eickhoff, J; Haug, BE; Isaksson, J; Hansen, EH Kinase Chemodiversity from the Arctic: The Breitfussins. J Med Chem62:10167-10181 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Aurora kinase B |
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| Name: | Aurora kinase B |
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| Synonyms: | AIK2 | AIM-1 | AIM1 | AIRK2 | ARK2 | AURKB | AURKB_HUMAN | Aurora B kinase (aurB) | Aurora B-INCENP | Aurora kinase 2 | Aurora kinase B (AURKB) | Aurora-related kinase 2 | STK-1 | STK1 | STK12 | STK5 | Serine/threonine-protein kinase aurora B |
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| Type: | Protein |
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| Mol. Mass.: | 39327.72 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q96GD4 |
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| Residue: | 344 |
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| Sequence: | MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMEN
SSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEH
QLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATI
MEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYL
PPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGA
QDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
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| BDBM50509368 |
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| n/a |
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| Name | BDBM50509368 |
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| Synonyms: | CHEMBL4475097 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H11Br2N3O2 |
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| Mol. Mass. | 437.085 |
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| SMILES | COc1cc(Br)cc2[nH]cc(-c3cnc(o3)-c3ccc(Br)[nH]3)c12 |
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| Structure | 
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