| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prolyl 4-hydroxylase |
|---|
| Ligand | BDBM107704 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1840409 (CHEMBL4340708) |
|---|
| IC50 | <1000±n/a nM |
|---|
| Citation |  Langley, GW; Abboud, MI; Lohans, CT; Schofield, CJ Inhibition of a viral prolyl hydroxylase. Bioorg Med Chem27:2405-2412 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prolyl 4-hydroxylase |
|---|
| Name: | Prolyl 4-hydroxylase |
|---|
| Synonyms: | A085R | Prolyl 4-hydroxylase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 27815.10 |
|---|
| Organism: | Paramecium bursaria Chlorella virus 1 |
|---|
| Description: | ChEMBL_119118 |
|---|
| Residue: | 242 |
|---|
| Sequence: | MTNKFISYNKMETREYLLTILFVIACFMVLNLERREGFETSDRPGVCDGKYYEKIDGFLS
DIECDVLINAAIKKGLIKSEVGGATENDPIKLDPKSRNSEQTWFMPGEHEVIDKIQKKTR
EFLNSKKHCIDKYNFEDVQVARYKPGQYYYHHYDGDDCDDACPKDQRLATLMVYLKAPEE
GGGGETDFPTLKTKIKPKKGTSIFFWVADPVTRKLYKETLHAGLPVKSGEKIIANQWIRA
VK
|
|
|
|---|
| BDBM107704 |
|---|
| n/a |
|---|
| Name | BDBM107704 |
|---|
| Synonyms: | US11426393, Compound Table XV.11 | US8598210, 119 | US8598210, Table XV, 10 | US8598210, Table XV, 11 | US8722895, 10: {[5-(3-Chlorophenyl)-3-hydroxypyridine-2- carbonyl]amino}-acetic acid trifluoroacetic acid salt | US8722895, 11: {[5-(3-Chlorophenyl)-3-hydroxypyridine-2- carbonyl]amino}-acetic acid | US9598370, Example 00136 | USRE47437, Example {[5-(3-Chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}-acetic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H11ClN2O4 |
|---|
| Mol. Mass. | 306.701 |
|---|
| SMILES | OC(=O)CNC(=O)c1ncc(cc1O)-c1cccc(Cl)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
