Reaction Details |
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Target | Sigma non-opioid intracellular receptor 1 |
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Ligand | BDBM50067023 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_200984 (CHEMBL873113) |
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IC50 | >10000±n/a nM |
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Citation | Berardi, F; Santoro, S; Perrone, R; Tortorella, V; Govoni, S; Lucchi, L N-[omega-(Tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine are highly potent and selective sigma1 or sigma2 ligands. J Med Chem41:3940-7 (1998) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Sigma non-opioid intracellular receptor 1 |
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Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 25266.54 |
Organism: | RAT |
Description: | Q9R0C9 |
Residue: | 223 |
Sequence: | MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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BDBM50067023 |
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n/a |
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Name | BDBM50067023 |
Synonyms: | 1-(3-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl)-3,3-dimethylpiperidine | 1-[3-(6-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-3,3-dimethyl-piperidine | CHEMBL128996 |
Type | Small organic molecule |
Emp. Form. | C21H33NO |
Mol. Mass. | 315.4928 |
SMILES | COc1ccc2C(CCCN3CCCC(C)(C)C3)CCCc2c1 |
Structure |
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