| Reaction Details |
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 | Report a problem with these data |
| Target | Inositol polyphosphate multikinase |
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| Ligand | BDBM50157555 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1868988 (CHEMBL4370054) |
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| IC50 | >30000±n/a nM |
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| Citation |  Gu, C; Stashko, MA; Puhl-Rubio, AC; Chakraborty, M; Chakraborty, A; Frye, SV; Pearce, KH; Wang, X; Shears, SB; Wang, H Inhibition of Inositol Polyphosphate Kinases by Quercetin and Related Flavonoids: A Structure-Activity Analysis. J Med Chem62:1443-1454 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Inositol polyphosphate multikinase |
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| Name: | Inositol polyphosphate multikinase |
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| Synonyms: | 2.7.1.140 | 2.7.1.151 | 2.7.1.153 | IMPK | IPMK | IPMK_HUMAN | Inositol 1,3,4,6-tetrakisphosphate 5-kinase | Inositol polyphosphate multikinase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47229.24 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_119151 |
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| Residue: | 416 |
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| Sequence: | MATEPPSPLRVEAPGPPEMRTSPAIESTPEGTPQPAGGRLRFLNGCVPLSHQVAGHMYGK
DKVGILQHPDGTVLKQLQPPPRGPRELEFYNMVYAADCFDGVLLELRKYLPKYYGIWSPP
TAPNDLYLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPLMEEIGFLVLG
MRVYHVHSDSYETENQHYGRSLTKETIKDGVSRFFHNGYCLRKDAVAASIQKIEKILQWF
ENQKQLNFYASSLLFVYEGSSQPTTTKLNDRTLAEKFLSKGQLSDTEVLEYNNNFHVLSS
TANGKIESSVGKSLSKMYARHRKIYTKKHHSQTSLKVENLEQDNGWKSMSQEHLNGNVLS
QLEKVFYHLPTGCQEIAEVEVRMIDFAHVFPSNTIDEGYVYGLKHLISVLRSILDN
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| BDBM50157555 |
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| n/a |
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| Name | BDBM50157555 |
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| Synonyms: | 2-(3,4-dihydroxyphenyl)-4H-chromen-4-one | 3',4'-dihydroxy flavone | 3',4'-dihydroxyflavone | CHEMBL222556 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H10O4 |
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| Mol. Mass. | 254.2375 |
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| SMILES | Oc1ccc(cc1O)-c1cc(=O)c2ccccc2o1 |
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| Structure | 
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