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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fatty-acid amide hydrolase 1 [30-579] | ||
| Ligand | BDBM143373 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1870781 (CHEMBL4371948) | ||
| IC50 | 1500±n/a nM | ||
| Citation |  Bhuniya, D; Kharul, RK; Hajare, A; Shaikh, N; Bhosale, S; Balwe, S; Begum, F; De, S; Athavankar, S; Joshi, D; Madgula, V; Joshi, K; Raje, AA; Meru, AV; Magdum, A; Mookhtiar, KA; Barbhaiya, R Discovery and evaluation of novel FAAH inhibitors in neuropathic pain model. Bioorg Med Chem Lett29:238-243 (2019) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fatty-acid amide hydrolase 1 [30-579] | |||
| Name: | Fatty-acid amide hydrolase 1 [30-579] | ||
| Synonyms: | Anandamide amidohydrolase 1 | FAAH1_RAT | Faah | Faah1 | Fatty Acid Amide Hydrolase | Fatty Acid Amide Hydrolic, FAAH | Fatty-acid amide hydrolase (FAAH) | Fatty-acid amide hydrolase 1 | Fatty-acid amide hydrolase 1 (FAAH) | Fatty-acid amide hydrolase 1 (aa 30-579) | Oleamide hydrolase 1 | ||
| Type: | Single-pass membrane protein; homodimer | ||
| Mol. Mass.: | 60474.00 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | P97612 (aa 30-579) | ||
| Residue: | 550 | ||
| Sequence: |
| ||
| BDBM143373 | |||
| n/a | |||
| Name | BDBM143373 | ||
| Synonyms: | US9682953, 20.A-10 | US9682953, 20.A-9 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H22F3N5O2 | ||
| Mol. Mass. | 469.459 | ||
| SMILES | Nc1ncc(cn1)C(=O)NC1CCC(CC1)=Cc1cccc(Oc2ccc(cn2)C(F)(F)F)c1 |(11.34,2.69,;10,1.93,;10,.38,;8.67,-.38,;7.34,.38,;7.34,1.93,;8.67,2.69,;6,-.38,;6,-1.93,;4.67,.38,;3.33,-.38,;3.33,-1.93,;2,-2.69,;.67,-1.93,;.67,-.38,;2,.38,;-.67,-2.69,;-2,-1.93,;-2,-.38,;-3.33,.38,;-4.67,-.38,;-4.67,-1.93,;-6,-2.69,;-7.34,-1.93,;-7.34,-.38,;-8.67,.38,;-10,-.38,;-10,-1.93,;-8.67,-2.69,;-11.34,.38,;-12.67,-.39,;-11.34,1.93,;-11.34,-1.16,;-3.33,-2.69,)| | ||
| Structure | 
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