| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-3 adrenergic receptor |
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| Ligand | BDBM50078804 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_38920 |
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| EC50 | 0.900000±n/a nM |
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| Citation |  Mathvink, RJ; Barritta, AM; Candelore, MR; Cascieri, MA; Deng, L; Tota, L; Strader, CD; Wyvratt, MJ; Fisher, MH; Weber, AE Potent, elective human beta3 adrenergic receptor agonists containing a substituted indoline-5-sulfonamide pharmacophore. Bioorg Med Chem Lett9:1869-74 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-3 adrenergic receptor |
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| Name: | Beta-3 adrenergic receptor |
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| Synonyms: | ADRB3 | ADRB3R | ADRB3_HUMAN | B3AR | Beta-2 adrenergic receptor and beta-3 adrenergic receptor | Beta-3 adrenoceptor | Beta-3 adrenoreceptor | adrenergic Beta3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 43534.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 408 |
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| Sequence: | MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
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| BDBM50078804 |
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| n/a |
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| Name | BDBM50078804 |
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| Synonyms: | 1-(4-hexyl-1,3-thiazol-2-yl)-N-phenyl-2,3-dihydro-1H-indole-5-sulfonamide | CHEMBL298594 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H27N3O2S2 |
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| Mol. Mass. | 441.609 |
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| SMILES | CCCCCCc1csc(n1)N1CCc2cc(ccc12)S(=O)(=O)Nc1ccccc1 |
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| Structure | 
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