| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50420428 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1903807 (CHEMBL4406029) |
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| Ki | 980±n/a nM |
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| Citation |  Tosh, DK; Salmaso, V; Rao, H; Bitant, A; Fisher, CL; Lieberman, DI; Vorbrüggen, H; Reitman, ML; Gavrilova, O; Gao, ZG; Auchampach, JA; Jacobson, KA Truncated (N)-Methanocarba Nucleosides as Partial Agonists at Mouse and Human A J Med Chem63:4334-4348 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3AR | AA3R_MOUSE | Adenosine A3 receptor | Adora3 | Gpcr2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36460.91 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1515686 |
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| Residue: | 319 |
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| Sequence: | MEADNTTETDWLNITYITMEAAIGLCAVVGNMLVIWVVKLNPTLRTTTVYFIVSLALADI
AVGVLVIPLAIAVSLQVKMHFYACLFMSCVLLIFTHASIMSLLAIAVHRYLRVKLTVRYR
TVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKATLASSQNSSTLLCHFRSVVSLDYMVF
FSFITWILVPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLF
ALCWLPLSIINFVSYFDVKIPDVAMCLGILLSHANSMMNPIVYACKIKKFKETYFLILRA
VRLCQTSDSLDSNMEQTTE
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| BDBM50420428 |
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| n/a |
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| Name | BDBM50420428 |
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| Synonyms: | CHEMBL2089347 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H24ClN5O2 |
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| Mol. Mass. | 485.965 |
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| SMILES | O[C@@H]1[C@@H]2C[C@@H]2[C@H]([C@@H]1O)n1cnc2c(NCCc3ccccc3)nc(nc12)C#Cc1ccccc1Cl |r| |
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| Structure | 
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