| Reaction Details |
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 | Report a problem with these data |
| Target | Cysteinyl leukotriene receptor 1 |
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| Ligand | BDBM50084793 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_52222 (CHEMBL663972) |
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| Ki | 86±n/a nM |
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| Citation |  Palomer, A; Pascual, J; Cabré, F; García, ML; Mauleón, D Derivation of pharmacophore and CoMFA models for leukotriene D(4) receptor antagonists of the quinolinyl(bridged)aryl series. J Med Chem43:392-400 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cysteinyl leukotriene receptor 1 |
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| Name: | Cysteinyl leukotriene receptor 1 |
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| Synonyms: | CLTR1_CAVPO | CYSLTR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 39007.58 |
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| Organism: | GUINEA PIG |
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| Description: | Leukotriene D4 0 GUINEA PIG::Q2NNR5 |
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| Residue: | 340 |
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| Sequence: | MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSA
FQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAM
SFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPP
QDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIV
VTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFF
SGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
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| BDBM50084793 |
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| n/a |
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| Name | BDBM50084793 |
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| Synonyms: | 4-Oxo-2-(1H-tetrazol-5-yl)-4H-chromene-8-carboxylic acid 4-(quinolin-2-ylmethoxy)-benzylamide | 4-oxo-N-(4-(quinolin-2-ylmethoxy)benzyl)-2-(1H-tetrazol-5-yl)-4H-chromene-8-carboxamide | CHEMBL131287 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H20N6O4 |
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| Mol. Mass. | 504.4962 |
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| SMILES | O=C(NCc1ccc(OCc2ccc3ccccc3n2)cc1)c1cccc2c1oc(cc2=O)-c1nnn[nH]1 |
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| Structure | 
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