| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine kinase |
|---|
| Ligand | BDBM50533826 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1927381 (CHEMBL4430453) |
|---|
| Ki | 25400±n/a nM |
|---|
| Citation |  Köse, M; Schiedel, AC; Bauer, AA; Poschenrieder, H; Burbiel, JC; Akkinepally, RR; Stachel, HD; Müller, CE Focused screening to identify new adenosine kinase inhibitors. Bioorg Med Chem24:5127-5133 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine kinase |
|---|
| Name: | Adenosine kinase |
|---|
| Synonyms: | ADK | ADK_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 40545.97 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1467841 |
|---|
| Residue: | 362 |
|---|
| Sequence: | MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAED
KHKELFDELVKKFKVEYHAGGSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKA
AEAHVDAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKAR
VCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGN
ETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFA
VLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPD
FH
|
|
|
|---|
| BDBM50533826 |
|---|
| n/a |
|---|
| Name | BDBM50533826 |
|---|
| Synonyms: | CHEMBL4520524 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H13N3O2 |
|---|
| Mol. Mass. | 315.3254 |
|---|
| SMILES | CN1C(=O)c2nc(nc(c2C1=O)-c1ccccc1)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
