| Reaction Details |
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 | Report a problem with these data |
| Target | Relaxin receptor 1 |
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| Ligand | BDBM50534450 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1929028 (CHEMBL4432204) |
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| EC50 | <10000±n/a nM |
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| Citation |  Hojo, K; Hossain, MA; Tailhades, J; Shabanpoor, F; Wong, LL; Ong-Pålsson, EE; Kastman, HE; Ma, S; Gundlach, AL; Rosengren, KJ; Wade, JD; Bathgate, RA Development of a Single-Chain Peptide Agonist of the Relaxin-3 Receptor Using Hydrocarbon Stapling. J Med Chem59:7445-56 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Relaxin receptor 1 |
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| Name: | Relaxin receptor 1 |
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| Synonyms: | LGR7 | Leucine-rich repeat-containing G-protein coupled receptor 7 | RXFP1 | RXFP1_HUMAN | Relaxin family peptide receptor 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 86990.83 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_818426 |
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| Residue: | 757 |
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| Sequence: | MTSGSVFFYILIFGKYFSHGGGQDVKCSLGYFPCGNITKCLPQLLHCNGVDDCGNQADED
NCGDNNGWSLQFDKYFASYYKMTSQYPFEAETPECLVGSVPVQCLCQGLELDCDETNLRA
VPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLY
LSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDK
PLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDEL
DLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQ
RMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVFVWVVSAVTC
FGNIFVICMRPYIRSENKLYAMSIISLCCADCLMGIYLFVIGGFDLKFRGEYNKHAQLWM
ESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCVRPGKCRTITVLILIWITGF
IVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTESIGAQIYSVAIFLGINLAAFIIIVFSYG
SMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALCWIPIFVVKFLSLLQVEIPGT
ITSWVVIFILPINSALNPILYTLTTRPFKEMIHRFWYNYRQRKSMDSKGQKTYAPSFIWV
EMWPLQEMPPELMKPDLFTYPCEMSLISQSTRLNSYS
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| BDBM50534450 |
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| n/a |
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| Name | BDBM50534450 |
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| Synonyms: | CHEMBL4573196 |
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| Type | Small organic molecule |
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| Emp. Form. | C96H149N29O26 |
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| Mol. Mass. | 2125.389 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| |
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| Structure | 
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