| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-glucuronidase |
|---|
| Ligand | BDBM23420 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1983554 (CHEMBL4616960) |
|---|
| IC50 | 1610000±n/a nM |
|---|
| Citation |  Awolade, P; Cele, N; Kerru, N; Gummidi, L; Oluwakemi, E; Singh, P Therapeutic significance of ?-glucuronidase activity and its inhibitors: A review. Eur J Med Chem187:0 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-glucuronidase |
|---|
| Name: | Beta-glucuronidase |
|---|
| Synonyms: | β-Glucuronidase | BGLR_ECOLI | Beta-glucuronidase (EcGUS) | gurA | gusA | uidA |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 68431.57 |
|---|
| Organism: | Escherichia coli (Enterobacteria) |
|---|
| Description: | P05804 |
|---|
| Residue: | 603 |
|---|
| Sequence: | MLRPVETPTREIKKLDGLWAFSLDRENCGIDQRWWESALQESRAIAVPGSFNDQFADADI
RNYAGNVWYQREVFIPKGWAGQRIVLRFDAVTHYGKVWVNNQEVMEHQGGYTPFEADVTP
YVIAGKSVRITVCVNNELNWQTIPPGMVITDENGKKKQSYFHDFFNYAGIHRSVMLYTTP
NTWVDDITVVTHVAQDCNHASVDWQVVANGDVSVELRDADQQVVATGQGTSGTLQVVNPH
LWQPGEGYLYELCVTAKSQTECDIYPLRVGIRSVAVKGEQFLINHKPFYFTGFGRHEDAD
LRGKGFDNVLMVHDHALMDWIGANSYRTSHYPYAEEMLDWADEHGIVVIDETAAVGFNLS
LGIGFEAGNKPKELYSEEAVNGETQQAHLQAIKELIARDKNHPSVVMWSIANEPDTRPQG
AREYFAPLAEATRKLDPTRPITCVNVMFCDAHTDTISDLFDVLCLNRYYGWYVQSGDLET
AEKVLEKELLAWQEKLHQPIIITEYGVDTLAGLHSMYTDMWSEEYQCAWLDMYHRVFDRV
SAVVGEQVWNFADFATSQGILRVGGNKKGIFTRDRKPKSAAFLLQKRWTGMNFGEKPQQG
GKQ
|
|
|
|---|
| BDBM23420 |
|---|
| n/a |
|---|
| Name | BDBM23420 |
|---|
| Synonyms: | 7,4′-Dihydroxy-isoflavone (3a) | 7-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one | CHEMBL8145 | Daidzein | US8552057, 7 |
|---|
| Type | isoflavone |
|---|
| Emp. Form. | C15H10O4 |
|---|
| Mol. Mass. | 254.2375 |
|---|
| SMILES | Oc1ccc(cc1)-c1coc2cc(O)ccc2c1=O |
|---|
| Structure | 
|
|---|
Search and Browse
