| Reaction Details |
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 | Report a problem with these data |
| Target | Transient receptor potential cation channel subfamily V member 4 |
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| Ligand | BDBM50545034 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1994275 (CHEMBL4628170) |
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| EC50 | 150±n/a nM |
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| Citation |  Lawhorn, BG; Brnardic, EJ; Behm, DJ Recent advances in TRPV4 agonists and antagonists. Bioorg Med Chem Lett30:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transient receptor potential cation channel subfamily V member 4 |
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| Name: | Transient receptor potential cation channel subfamily V member 4 |
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| Synonyms: | TRPV4_MOUSE | Trp12 | Trpv4 | Vrl2 | Vroac |
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| Type: | PROTEIN |
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| Mol. Mass.: | 98032.61 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1514430 |
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| Residue: | 871 |
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| Sequence: | MADPGDGPRAAPGEVAEPPGDESGTSGGEAFPLSSLANLFEGEEGSSSLSPVDASRPAGP
GDGRPNLRMKFQGAFRKGVPNPIDLLESTLYESSVVPGPKKAPMDSLFDYGTYRHHPSDN
KRWRRKVVEKQPQSPKAPAPQPPPILKVFNRPILFDIVSRGSTADLDGLLSFLLTHKKRL
TDEEFREPSTGKTCLPKALLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQT
SLHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHI
VNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCSRLFPDS
NLETVLNNDGLSPLMMAAKTGKIGVFQHIIRREVTDEDTRHLSRKFKDWAYGPVYSSLYD
LSSLDTCGEEVSVLEILVYNSKIENRHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLC
AMVIFTLTAYYQPLEGTPPYPYRTTVDYLRLAGEVITLFTGVLFFFTSIKDLFTKKCPGV
NSLFVDGSFQLLYFIYSVLVVVSAALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTG
TYSIMIQKILFKDLFRFLLVYLLFMIGYASALVTLLNPCTNMKVCDEDQSNCTVPTYPAC
RDSETFSAFLLDLFKLTIGMGDLEMLSSAKYPVVFILLLVTYIILTFVLLLNMLIALMGE
TVGQVSKESKHIWKLQWATTILDIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRV
DEVNWSHWNQNLGIINEDPGKSEIYQYYGFSHTVGRLRRDRWSSVVPRVVELNKNSSADE
VVVPLDNLGNPNCDGHQQGYAPKWRTDDAPL
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| BDBM50545034 |
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| n/a |
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| Name | BDBM50545034 |
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| Synonyms: | CHEBI:34450 | CHEMBL1893588 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H32O3 |
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| Mol. Mass. | 320.4663 |
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| SMILES | CCCCC\C=C/C\C=C/C\C=C/CC1OC1CCCC(O)=O |
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| Structure | 
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