| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
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| Ligand | BDBM50551368 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2031243 (CHEMBL4685401) |
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| Ki | 38±n/a nM |
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| Citation |  Bucki, A; Marcinkowska, M; ?niecikowska, J; Zagórska, A; Jamrozik, M; Paw?owski, M; G?uch-Lutwin, M; Siwek, A; Jakubczyk, M; Pytka, K; Jastrz?bska-Wi?sek, M; Partyka, A; Weso?owska, A; Mierzejewski, P; Ko?aczkowski, M Multifunctional 6-fluoro-3-[3-(pyrrolidin-1-yl)propyl]-1,2-benzoxazoles targeting behavioral and psychological symptoms of dementia (BPSD). Eur J Med Chem191:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 6 |
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| Name: | 5-hydroxytryptamine receptor 6 |
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| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 46968.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50406 |
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| Residue: | 440 |
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| Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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| BDBM50551368 |
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| n/a |
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| Name | BDBM50551368 |
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| Synonyms: | CHEMBL4762226 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22FN3O3S2 |
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| Mol. Mass. | 459.557 |
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| SMILES | Fc1ccc2cc(sc2c1)S(=O)(=O)N[C@H]1CCN(CCCc2noc3ccccc23)C1 |r| |
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| Structure | 
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