| Reaction Details |
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 | Report a problem with these data |
| Target | Cholecystokinin receptor type A |
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| Ligand | BDBM50422148 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2033591 (CHEMBL4687749) |
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| IC50 | 155±n/a nM |
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| Citation |  Talele, TT Opportunities for Tapping into Three-Dimensional Chemical Space through a Quaternary Carbon. J Med Chem63:13291-13315 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholecystokinin receptor type A |
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| Name: | Cholecystokinin receptor type A |
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| Synonyms: | CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_HUMAN | CCKRA | Cholecystokinin receptor | Cholecystokinin receptor type A | Cholecystokinin-1 Receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 47859.34 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Stable expression of human CCK-1 receptors in HEK 293 cells. |
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| Residue: | 428 |
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| Sequence: | MDVVDSLLVNGSNITPPCELGLENETLFCLDQPRPSKEWQPAVQILLYSLIFLLSVLGNT
LVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYF
MGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYS
NLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIPGIVMMVAYGLISLELYQGI
KFEASQKKSAKERKPSTTSSGKYEDSDGCYLQKTRPPRKLELRQLSTGSSSRANRIRSNS
SAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTASAERRLSGTPISFILLLSY
TSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGARGEVGEEEEGGTTGASLSRFSYSH
MSASVPPQ
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| BDBM50422148 |
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| n/a |
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| Name | BDBM50422148 |
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| Synonyms: | CHEMBL317181 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H32N4O4 |
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| Mol. Mass. | 560.6423 |
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| SMILES | CC(C)N(C(=O)CN1c2ccccc2N(c2ccccc2)C(=O)C(CC(=O)Nc2ccccc2)C1=O)c1ccccc1 |
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| Structure | 
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