| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50553410 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2046330 (CHEMBL4701029) |
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| IC50 | 20±n/a nM |
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| Citation |  Yu, F; Zhu, C; Xie, Q; Wang, Y Adenosine A J Med Chem63:12196-12212 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50553410 |
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| n/a |
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| Name | BDBM50553410 |
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| Synonyms: | CHEMBL4741609 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H23F2N9O3S |
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| Mol. Mass. | 555.56 |
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| SMILES | NC(=O)Cc1cc(N2CCN(CCn3c4nc(N)n5nc(nc5c4sc3=O)-c3ccco3)CC2)c(F)cc1F |
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| Structure | 
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