| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 4 |
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| Ligand | BDBM50556833 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2057467 (CHEMBL4712468) |
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| Ki | 965±n/a nM |
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| Citation |  Akgul, O; Singh, S; Andring, JT; McKenna, R; Selleri, S; Carta, F; Angeli, A; Supuran, CT Handling drug-target selectivity: A study on ureido containing Carbonic Anhydrase inhibitors. Eur J Med Chem212:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 4 |
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| Name: | Carbonic anhydrase 4 |
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| Synonyms: | CA-IV | CA4 | CAH4_HUMAN | Carbonate dehydratase IV | Carbonic anhydrase | Carbonic anhydrase 4 (CA IV) | Carbonic anhydrase IV (CA IV) |
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| Type: | Enzyme |
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| Mol. Mass.: | 35037.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P22748 |
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| Residue: | 312 |
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| Sequence: | MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTK
AKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSD
LPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGF
QPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFRE
PIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLG
PMLACLLAGFLR
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| BDBM50556833 |
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| n/a |
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| Name | BDBM50556833 |
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| Synonyms: | CHEMBL4751791 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H22N4O5S2 |
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| Mol. Mass. | 426.51 |
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| SMILES | Cc1cc(C)cc(NC(=O)NCCS(=O)(=O)Nc2ccc(cc2)S(N)(=O)=O)c1 |
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| Structure | 
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