| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50120944 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_60696 (CHEMBL676506) |
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| Ki | >1000±n/a nM |
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| Citation |  Liégeois, JF; Eyrolles, L; Ellenbroek, BA; Lejeune, C; Carato, P; Bruhwyler, J; Géczy, J; Damas, J; Delarge, J New pyridobenzodiazepine derivatives: modifications of the basic side chain differentially modulate binding to dopamine (D(4.2), D(2L)) and serotonin (5-HT(2A)) receptors. J Med Chem45:5136-49 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM50120944 |
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| n/a |
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| Name | BDBM50120944 |
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| Synonyms: | CHEMBL149493 | N,N-Dimethyl-N'-(8-methyl-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6-yl)-ethane-1,2-diamine |
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| Type | Small organic molecule |
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| Emp. Form. | C17H21N5 |
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| Mol. Mass. | 295.3821 |
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| SMILES | CN(C)CCNC1=Nc2cccnc2Nc2ccc(C)cc12 |t:6| |
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| Structure | 
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