| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 4 |
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| Ligand | BDBM50562200 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2077676 (CHEMBL4733467) |
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| Ki | >100000±n/a nM |
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| Citation |  Bouzina, A; Berredjem, M; Nocentini, A; Bua, S; Bouaziz, Z; Jose, J; Le Borgne, M; Marminon, C; Gratteri, P; Supuran, CT Ninhydrins inhibit carbonic anhydrases directly binding to the metal ion. Eur J Med Chem209:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 4 |
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| Name: | Carbonic anhydrase 4 |
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| Synonyms: | CA-IV | CA4 | CAH4_HUMAN | Carbonate dehydratase IV | Carbonic anhydrase | Carbonic anhydrase 4 (CA IV) | Carbonic anhydrase IV (CA IV) |
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| Type: | Enzyme |
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| Mol. Mass.: | 35037.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P22748 |
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| Residue: | 312 |
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| Sequence: | MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTK
AKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSD
LPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGF
QPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFRE
PIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLG
PMLACLLAGFLR
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| BDBM50562200 |
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| n/a |
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| Name | BDBM50562200 |
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| Synonyms: | CHEMBL4754929 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H5NO6 |
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| Mol. Mass. | 223.1391 |
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| SMILES | OC1(O)C(=O)c2ccc(cc2C1=O)[N+]([O-])=O |
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| Structure | 
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