| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2C |
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| Ligand | BDBM50132115 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2829 (CHEMBL621515) |
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| Ki | 990±n/a nM |
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| Citation |  Khorana, N; Smith, C; Herrick-Davis, K; Purohit, A; Teitler, M; Grella, B; Dukat, M; Glennon, RA Binding of tetrahydrocarboline derivatives at human 5-HT5A receptors. J Med Chem46:3930-7 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2C |
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| Name: | 5-hydroxytryptamine receptor 2C |
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| Synonyms: | 5-HT2C | 5-hydroxytryptamine receptor 2C | 5-hydroxytryptamine receptor 2C (5HT2c) | 5HT2C_RAT | 5ht1c | Htr1c | Htr2c | Serotonin (5-HT) receptor | Serotonin receptor 2a and 2c (5HT2A and 5HT2C) |
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| Type: | Enzyme |
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| Mol. Mass.: | 51935.10 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P08909 |
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| Residue: | 460 |
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| Sequence: | MVNLGNAVRSLLMHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALS
IVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYV
WPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVW
AISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIY
VLRRQTLMLLRGHTEEELANMSLNFLNCCCKKNGGEEENAPNPNPDQKPRRKKKEKRPRG
TMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGY
VCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRH
TNERVARKANDPEPGIEMQVENLELPVNPSNVVSERISSV
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| BDBM50132115 |
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| n/a |
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| Name | BDBM50132115 |
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| Synonyms: | 2-[4-(4-Methoxy-phenyl)-butyl]-5-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole | CHEMBL128945 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H28N2O |
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| Mol. Mass. | 348.4812 |
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| SMILES | COc1ccc(CCCCN2CCc3c(C2)c2ccccc2n3C)cc1 |
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| Structure | 
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