| Reaction Details |
|---|
 | Report a problem with these data |
| Target | P2Y purinoceptor 6 |
|---|
| Ligand | BDBM50571222 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2114153 (CHEMBL4823003) |
|---|
| EC50 | 549±n/a nM |
|---|
| Citation |  Oliva, P; Scortichini, M; Dobelmann, C; Jain, S; Gopinatth, V; Toti, KS; Phung, NB; Junker, A; Jacobson, KA Structure-activity relationships of pyrimidine nucleotides containing a 5'-?,?-methylene diphosphonate at the P2Y Bioorg Med Chem Lett45:0 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| P2Y purinoceptor 6 |
|---|
| Name: | P2Y purinoceptor 6 |
|---|
| Synonyms: | P2RY6 | P2RY6_HUMAN | P2Y purinoceptor 6 | P2Y6 | Pyrimidinergic receptor P2Y6 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 36452.29 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1511151 |
|---|
| Residue: | 328 |
|---|
| Sequence: | MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTR
TAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCI
SFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDL
SPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARM
AVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPIL
FYFTQKKFRRRPHELLQKLTAKWQRQGR
|
|
|
|---|
| BDBM50571222 |
|---|
| n/a |
|---|
| Name | BDBM50571222 |
|---|
| Synonyms: | CHEMBL4871928 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H52FN5O11P2 |
|---|
| Mol. Mass. | 727.696 |
|---|
| SMILES | CCN(CC)CC.CCN(CC)CC.O[C@@H]1[C@@H](COP(O)(=O)CP(O)(O)=O)O[C@H]([C@@H]1O)n1cc(F)\c(=N\OCc2ccccc2)[nH]c1=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
