| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily A member 3 |
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| Ligand | BDBM50145062 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_214956 (CHEMBL821185) |
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| Kd | 100±n/a nM |
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| Citation |  Baell, JB; Gable, RW; Harvey, AJ; Toovey, N; Herzog, T; Hänsel, W; Wulff, H Khellinone derivatives as blockers of the voltage-gated potassium channel Kv1.3: synthesis and immunosuppressive activity. J Med Chem47:2326-36 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium voltage-gated channel subfamily A member 3 |
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| Name: | Potassium voltage-gated channel subfamily A member 3 |
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| Synonyms: | HGK5 | HLK3 | HPCN3 | HuKIII | KCNA3 | KCNA3_HUMAN | Potassium voltage-gated channel subfamily A member 3 | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv1.3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 63835.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1513935 |
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| Residue: | 575 |
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| Sequence: | MDERLSLLRSPPPPSARHRAHPPQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDH
LLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLK
TLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIF
SEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVS
VLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVET
LCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSL
AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
ADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIV
SNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHS
AFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
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| BDBM50145062 |
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| n/a |
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| Name | BDBM50145062 |
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| Synonyms: | 1-[12b-hydroxy-1b,3a,10b-trimethyl-2,3,4,5-tetra(methylcarbonyloxy)-14-methylene-1a-methyloxycarbonyl-8-oxo-1a,1b,2,3,3a,3b,4,5,5a,6,8,10a,10b,11,12,12a,12b,13,14,14a-icosahydrooxireno[2',3':7,8]chryseno[2,1-c]oxepin-5-yl]ethyl acetate | CHEMBL311283 |
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| Type | Small organic molecule |
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| Emp. Form. | C40H52O16 |
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| Mol. Mass. | 788.8313 |
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| SMILES | COC(=O)C12O[C@@H]1C(=C)C[C@@]1(O)[C@@H]3CC[C@@]4(C)[C@@H]5C=CC(=O)OC[C@]5(C(C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]4[C@@]3(C)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@@]21C |c:19| |
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| Structure | 
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