| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Elongin-C |
|---|
| Ligand | BDBM50459878 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2195888 (CHEMBL5108404) |
|---|
| IC50 | 1214±n/a nM |
|---|
| Citation |  de Castro, GV; Ciulli, A Estimating the cooperativity of PROTAC-induced ternary complexes using RSC Med Chem12:1765-1770 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Elongin-C |
|---|
| Name: | Elongin-C |
|---|
| Synonyms: | ELOC | ELOC_HUMAN | Elongin 15 kDa subunit | Elongin-C | RNA polymerase II transcription factor SIII subunit C | SIII p15 | TCEB1 | Transcription elongation factor B polypeptide 1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 12466.49 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_108414 |
|---|
| Residue: | 112 |
|---|
| Sequence: | MDGEEKTYGGCEGPDAMYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEV
NFREIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC
|
|
|
|---|
| BDBM50459878 |
|---|
| n/a |
|---|
| Name | BDBM50459878 |
|---|
| Synonyms: | CHEMBL4227834 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C53H62ClN7O8S |
|---|
| Mol. Mass. | 992.619 |
|---|
| SMILES | C[C@H]1C[C@@H](Nc2ccc(Cl)cc2)c2cc(ccc2N1C(C)=O)-c1ccc(cc1)C(=O)NCCOCCOCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C |r| |
|---|
| Structure | 
|
|---|
Search and Browse
