| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50592426 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2204129 (CHEMBL5116837) |
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| Ki | 6.0±n/a nM |
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| Citation |  Levoin, N; Murthy, AVR; Narendar, V; Kumar, NS; Aparna, P; Bhavani, AKD; Reddy, CR; Mosset, P; Grée, R Discovery of potent dual ligands for dopamine D4 and ?1 receptors. Bioorg Med Chem69:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM50592426 |
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| n/a |
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| Name | BDBM50592426 |
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| Synonyms: | CHEMBL4547253 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22BrFN4 |
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| Mol. Mass. | 429.329 |
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| SMILES | Fc1ccc(CN2CCC(CC2)n2cc(Cc3ccc(Br)cc3)nn2)cc1 |
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| Structure | 
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