| Reaction Details |
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 | Report a problem with these data |
| Target | Matrilysin |
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| Ligand | BDBM50592902 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2206239 (CHEMBL5118947) |
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| IC50 | >100±n/a nM |
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| Citation |  Baidya, SK; Banerjee, S; Adhikari, N; Jha, T Selective Inhibitors of Medium-Size S1' Pocket Matrix Metalloproteinases: A Stepping Stone of Future Drug Discovery. J Med Chem65:10709-10754 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Matrilysin |
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| Name: | Matrilysin |
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| Synonyms: | MMP7 | MMP7_HUMAN | MPSL1 | Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7) | Matrix metalloproteinase-7 (MMP7) | PUMP1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 29681.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P09237 |
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| Residue: | 267 |
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| Sequence: | MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK
EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL
PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF
APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD
PQNFKLSQDDIKGIQKLYGKRSNSRKK
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| BDBM50592902 |
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| n/a |
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| Name | BDBM50592902 |
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| Synonyms: | CHEMBL5198463 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H24N4O5S |
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| Mol. Mass. | 504.558 |
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| SMILES | ONC(=O)C1(CCOCC1)S(=O)(=O)c1ccc(cc1)-n1cc(nn1)-c1ccc(cc1)-c1ccccc1 |
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| Structure | 
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