| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50166021 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303136 (CHEMBL829064) |
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| Ki | 7156±n/a nM |
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| Citation |  Ding, K; Chen, J; Ji, M; Wu, X; Varady, J; Yang, CY; Lu, Y; Deschamps, JR; Levant, B; Wang, S Enantiomerically pure hexahydropyrazinoquinolines as potent and selective dopamine 3 subtype receptor ligands. J Med Chem48:3171-81 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DOPAMINE D3 | DRD3_RAT | Dopamine D3 receptor | Drd3 |
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| Type: | Protein |
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| Mol. Mass.: | 49540.58 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P19020 |
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| Residue: | 446 |
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| Sequence: | MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSI
CSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQ
QSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLK
RYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGP
LQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYV
NSALNPVIYTTFNVEFRKAFLKILSC
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| BDBM50166021 |
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| n/a |
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| Name | BDBM50166021 |
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| Synonyms: | CHEMBL193300 | Naphthalene-2-carboxylic acid {1-[2-((S)-8-methoxy-1,2,4,4a,5,6-hexahydro-pyrazino[1,2-a]quinolin-3-yl)-ethyl]-piperidin-4-yl}-amide |
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| Type | Small organic molecule |
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| Emp. Form. | C31H38N4O2 |
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| Mol. Mass. | 498.659 |
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| SMILES | COc1ccc2N3CCN(CCN4CCC(CC4)NC(=O)c4ccc5ccccc5c4)C[C@@H]3CCc2c1 |
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| Structure | 
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