| Reaction Details |
|---|
 | Report a problem with these data |
| Target | P2X purinoceptor 1 |
|---|
| Ligand | BDBM50594504 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2213098 (CHEMBL5126047) |
|---|
| IC50 | <100000±n/a nM |
|---|
| Citation |  Isaak, A; Dobelmann, C; Füsser, FT; Erlitz, KS; Koch, O; Junker, A Unveiling the Structure-Activity Relationships at the Orthosteric Binding Site of P2X Ion Channels: The Route to Selectivity. J Med Chem65:11291-11308 (2022) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| P2X purinoceptor 1 |
|---|
| Name: | P2X purinoceptor 1 |
|---|
| Synonyms: | ATP receptor | P2RX1 | P2RX1_HUMAN | P2X1 | Purinergic receptor | Purinergic, P2X |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 44992.65 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Purinergic, P2X 0 HUMAN::P51575 |
|---|
| Residue: | 399 |
|---|
| Sequence: | MARRFQEELAAFLFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFLYEKGYQTSSG
LISSVSVKLKGLAVTQLPGLGPQVWDVADYVFPAQGDNSFVVMTNFIVTPKQTQGYCAEH
PEGGICKEDSGCTPGKAKRKAQGIRTGKCVAFNDTVKTCEIFGWCPVEVDDDIPRPALLR
EAENFTLFIKNSISFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQESG
QNFSTLAEKGGVVGITIDWHCDLDWHVRHCRPIYEFHGLYEEKNLSPGFNFRFARHFVEN
GTNYRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKR
HYYKQKKFKYAEDMGPGAAERDLAATSSTLGLQENMRTS
|
|
|
|---|
| BDBM50594504 |
|---|
| n/a |
|---|
| Name | BDBM50594504 |
|---|
| Synonyms: | CHEMBL5170556 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H15N4O14P3 |
|---|
| Mol. Mass. | 508.1658 |
|---|
| SMILES | O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1c2ncncc2[nH]c1=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
