| Reaction Details |
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 | Report a problem with these data |
| Target | Casein kinase II subunit alpha 3 |
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| Ligand | BDBM50594806 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2214256 (CHEMBL5127388) |
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| IC50 | 3200±n/a nM |
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| Citation |  Tahtouh, T; Durieu, E; Villiers, B; Bruyère, C; Nguyen, TL; Fant, X; Ahn, KH; Khurana, L; Deau, E; Lindberg, MF; Sévère, E; Miege, F; Roche, D; Limanton, E; L'Helgoual'ch, JM; Burgy, G; Guiheneuf, S; Herault, Y; Kendall, DA; Carreaux, F; Bazureau, JP; Meijer, L Structure-Activity Relationship in the Leucettine Family of Kinase Inhibitors. J Med Chem65:1396-1417 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Casein kinase II subunit alpha 3 |
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| Name: | Casein kinase II subunit alpha 3 |
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| Synonyms: | 2.7.11.1 | CK II alpha 3 | CSK23_HUMAN | CSNK2A1P | CSNK2A3 | Casein kinase II alpha 1 polypeptide pseudogene | Casein kinase II subunit alpha 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45229.76 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_116899 |
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| Residue: | 391 |
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| Sequence: | MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT
NNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTD
FKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE
FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWRLGCMLASMIFRKEPFFHGRDNYD
QLVRIAKFLGTEDLYGYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDF
LDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANVMSGISSVPT
PSPLGPLAGSPVIAAANPLGMPVPAATGAQQ
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| BDBM50594806 |
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| n/a |
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| Name | BDBM50594806 |
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| Synonyms: | CHEMBL5176573 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12FN3O |
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| Mol. Mass. | 281.2844 |
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| SMILES | Fc1ccc(\C=C2/N=C(Nc3ccccc3)NC2=O)cc1 |t:7| |
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| Structure | 
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