| Reaction Details |
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 | Report a problem with these data |
| Target | Ceramide glucosyltransferase |
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| Ligand | BDBM50602025 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2238985 (CHEMBL5152881) |
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| IC50 | 1.8±n/a nM |
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| Citation |  Wang, J; Reynolds, M; Ibáñez, I; Sasaki, Y; Tanaka, Y; Kikuchi, F; Ohashi, T; Sato, S; Miyabayashi, M; Fujii, T; Tanaka, Y Photoredox-based late-stage functionalization in SAR study for in vivo potent glucosylceramide synthase inhibitor. Bioorg Med Chem Lett77:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ceramide glucosyltransferase |
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| Name: | Ceramide glucosyltransferase |
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| Synonyms: | CEGT_MOUSE | Ugcg |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44844.15 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_809643 |
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| Residue: | 394 |
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| Sequence: | MALLDLAQEGMALFGFVLFVVLWLMHFMSIIYTRLHLNKKATDKQPYSKLPGVSLLKPLK
GVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIDVCKKLLGKYPNVDARLFIGGKKVG
INPKINNLMPAYEVAKYDLIWICDSGIRVIPDTLTDMVNQMTEKVGLVHGLPYVADRQGF
AATLEQVYFGTSHPRSYISANVTGFKCVTGMSCLMRKDVLDQAGGLIAFAQYIAEDYFMA
KAIADRGWRFSMSTQVAMQNSGSYSISQFQSRMIRWTKLRINMLPATIICEPISECFVAS
LIIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQGGTLCFSKLDYAVAWFIRESMT
IYIFLSALWDPTISWRTGRYRLRCGGTAEEILDV
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| BDBM50602025 |
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| n/a |
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| Name | BDBM50602025 |
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| Synonyms: | CHEMBL5181454 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H27F3N2O4 |
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| Mol. Mass. | 512.5202 |
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| SMILES | CC(C)(O)c1ccc(cc1)N1Cc2c(cc(nc2-c2ccccc2OCC(F)(F)F)C2(C)COC2)C1=O |
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| Structure | 
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