| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50602676 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2241768 (CHEMBL5155978) |
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| Ki | 5800±n/a nM |
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| Citation |  Tosh, DK; Salmaso, V; Campbell, RG; Rao, H; Bitant, A; Pottie, E; Stove, CP; Liu, N; Gavrilova, O; Gao, ZG; Auchampach, JA; Jacobson, KA A Eur J Med Chem228:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_MOUSE | Adenosine A1 receptor | Adenosine receptor A1 | Adora1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36646.06 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_479902 |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSEVEQAWIANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIEEDIPEEKADD
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| BDBM50602676 |
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| n/a |
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| Name | BDBM50602676 |
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| Synonyms: | CHEMBL5207208 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H28F2N6O5 |
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| Mol. Mass. | 590.5773 |
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| SMILES | CNC(=O)[C@@]12C[C@@H]1[C@H]([C@H](O)[C@@H]2O)n1cnc2c(NCCc3ccc(O)c(OC)c3)nc(nc12)C#Cc1ccc(F)c(F)c1 |r| |
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| Structure | 
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