| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histone deacetylase 3 |
|---|
| Ligand | BDBM50613613 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2292699 |
|---|
| IC50 | 4890±n/a nM |
|---|
| Citation |  Roche, J; Bertrand, P Inside HDACs with more selective HDAC inhibitors. Eur J Med Chem121:451-483 (2016) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histone deacetylase 3 |
|---|
| Name: | Histone deacetylase 3 |
|---|
| Synonyms: | HD3 | HDAC3 | HDAC3_HUMAN | Histone deacetylase 3 (HDAC3) | Human HDAC3 | RPD3-2 | SMAP45 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 48829.55 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | O15379 |
|---|
| Residue: | 428 |
|---|
| Sequence: | MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCR
FHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNN
KICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEA
FYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVI
NQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTV
RNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQ
TIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDN
DKESDVEI
|
|
|
|---|
| BDBM50613613 |
|---|
| n/a |
|---|
| Name | BDBM50613613 |
|---|
| Synonyms: | CHEMBL5271192 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H25N3O2S |
|---|
| Mol. Mass. | 347.475 |
|---|
| SMILES | CN(C)c1cccc2c(SNCCCCCC(=O)NO)cccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
