| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain-containing protein 3 |
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| Ligand | BDBM50615276 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2301502 |
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| Kd | 4400±n/a nM |
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| Citation |  Crawford, TD; Vartanian, S; Côté, A; Bellon, S; Duplessis, M; Flynn, EM; Hewitt, M; Huang, HR; Kiefer, JR; Murray, J; Nasveschuk, CG; Pardo, E; Romero, FA; Sandy, P; Tang, Y; Taylor, AM; Tsui, V; Wang, J; Wang, S; Zawadzke, L; Albrecht, BK; Magnuson, SR; Cochran, AG; Stokoe, D Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance. Bioorg Med Chem Lett27:3534-3541 (2017) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Bromodomain-containing protein 3 |
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| Name: | Bromodomain-containing protein 3 |
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| Synonyms: | BRD3 | BRD3_HUMAN | Bromodomain and extra-terminal motif (BET) | Bromodomain-containing protein 3 | Bromodomain-containing protein 3 (BRD3) | KIAA0043 | RING3-like protein | RING3L |
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| Type: | Protein |
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| Mol. Mass.: | 79571.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q15059 |
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| Residue: | 726 |
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| Sequence: | MSTATTVAPAGIPATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFY
QPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTD
DIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPA
TPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKK
GVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQ
HAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLST
VKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPV
EAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAAL
SQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKA
NSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQ
SREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEEL
AQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSS
DSSDSE
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| BDBM50615276 |
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| n/a |
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| Name | BDBM50615276 |
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| Synonyms: | CHEMBL5270178 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H23N3O3 |
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| Mol. Mass. | 377.4363 |
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| SMILES | C\C=C\Cn1cc(-c2ccc(cc2)C(=O)N2CCOCC2)c2cc[nH]c2c1=O |
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| Structure | 
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