| Reaction Details |
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 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 2 |
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| Ligand | BDBM50208765 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_443348 (CHEMBL893596) |
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| Ki | 120000±n/a nM |
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| Citation |  Jørgensen, CG; Bräuner-Osborne, H; Nielsen, B; Kehler, J; Clausen, RP; Krogsgaard-Larsen, P; Madsen, U Novel 5-substituted 1-pyrazolol analogues of ibotenic acid: synthesis and pharmacology at glutamate receptors. Bioorg Med Chem15:3524-38 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Metabotropic glutamate receptor 2 |
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| Name: | Metabotropic glutamate receptor 2 |
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| Synonyms: | GPRC1B | GRM2 | GRM2_HUMAN | MGLUR2 | Metabotropic glutamate receptor | glutamate receptor, metabotropic 2 precursor | mGlu2 | metabotropic glutamate 2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 95584.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q14416 |
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| Residue: | 872 |
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| Sequence: | MGSLLALLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQ
RLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHI
CPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDY
FARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEK
VGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGAL
ESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFRQR
DCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMRPVNGRRLYK
DFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTL
DTSLIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADC
GLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKA
SGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARI
FGGAREGAQRPRFISPASQVAICLALISGQLLIVVAWLVVEAPGTGKETAPERREVVTLR
CNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIF
YVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNVVSHRAPTSRFGSAAA
RASSSLGQGSGSQFVPTVCNGREVVDSTTSSL
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| BDBM50208765 |
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| n/a |
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| Name | BDBM50208765 |
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| Synonyms: | (RS)-2-amino-(5-benzyl-1-hydroxy-4-pyrazolyl)acetic acid | CHEMBL444101 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H13N3O3 |
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| Mol. Mass. | 247.2499 |
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| SMILES | NC(C(O)=O)c1cnn(O)c1Cc1ccccc1 |w:1.0| |
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| Structure | 
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