Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Melanocortin receptor 5 | ||
| Ligand | BDBM50217655 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_448695 (CHEMBL897841) | ||
| Ki | 6100±n/a nM | ||
| Citation |  Mutulis, F; Kreicberga, J; Yahorava, S; Mutule, I; Borisova-Jan, L; Yahorau, A; Muceniece, R; Azena, S; Veiksina, S; Petrovska, R; Wikberg, JE Design and synthesis of a library of tertiary amides: evaluation as mimetics of the melanocortins' active core. Bioorg Med Chem15:5787-810 (2007) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Melanocortin receptor 5 | |||
| Name: | Melanocortin receptor 5 | ||
| Synonyms: | MC-2 | MC5-R | MC5R | MC5R_HUMAN | Melanocortin MC5 | Melanocortin receptor (M4 and M5) | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 36612.92 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P33032 | ||
| Residue: | 325 | ||
| Sequence: |
| ||
| BDBM50217655 | |||
| n/a | |||
| Name | BDBM50217655 | ||
| Synonyms: | CHEMBL238149 | N-(3-guanidino-propyl)-4-(1H-indol-3-yl)-N-naphthalen-2-ylmethyl-butyramide | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H31N5O | ||
| Mol. Mass. | 441.5679 | ||
| SMILES | NC(N)=NCCCN(Cc1ccc2ccccc2c1)C(=O)CCCc1c[nH]c2ccccc12 |(12.1,-27.56,;13.64,-27.56,;14.41,-26.24,;14.41,-28.9,;13.11,-29.73,;13.19,-31.27,;14.56,-31.97,;14.64,-33.51,;13.31,-34.45,;11.91,-33.63,;10.51,-34.44,;9.1,-33.62,;9.11,-31.99,;7.71,-31.18,;7.71,-29.56,;9.13,-28.75,;10.53,-29.57,;10.52,-31.19,;11.9,-32.11,;15.97,-34.25,;16,-35.78,;17.29,-33.46,;18.64,-34.21,;19.96,-33.42,;21.3,-34.16,;21.2,-35.7,;22.62,-36.27,;23.61,-35.09,;25.14,-35.03,;25.85,-33.68,;25.03,-32.38,;23.51,-32.44,;22.8,-33.79,)| | ||
| Structure | 
| ||