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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Melanocortin receptor 5 | ||
| Ligand | BDBM50217729 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_448695 (CHEMBL897841) | ||
| Ki | 8400±n/a nM | ||
| Citation |  Mutulis, F; Kreicberga, J; Yahorava, S; Mutule, I; Borisova-Jan, L; Yahorau, A; Muceniece, R; Azena, S; Veiksina, S; Petrovska, R; Wikberg, JE Design and synthesis of a library of tertiary amides: evaluation as mimetics of the melanocortins' active core. Bioorg Med Chem15:5787-810 (2007) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Melanocortin receptor 5 | |||
| Name: | Melanocortin receptor 5 | ||
| Synonyms: | MC-2 | MC5-R | MC5R | MC5R_HUMAN | Melanocortin MC5 | Melanocortin receptor (M4 and M5) | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 36612.92 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P33032 | ||
| Residue: | 325 | ||
| Sequence: |
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| BDBM50217729 | |||
| n/a | |||
| Name | BDBM50217729 | ||
| Synonyms: | CHEMBL237920 | N-((1R,4r)-4-(((1r,4R)-4-aminocyclohexyl)methyl)cyclohexyl)-N-((Z)-2-chloro-3-phenylallyl)-4-(1H-indol-3-yl)butanamide | ||
| Type | Small organic molecule | ||
| Emp. Form. | C34H44ClN3O | ||
| Mol. Mass. | 546.186 | ||
| SMILES | N[C@H]1CC[C@H](C[C@H]2CC[C@@H](CC2)N(C\C(Cl)=C\c2ccccc2)C(=O)CCCc2c[nH]c3ccccc23)CC1 |wU:6.5,4.4,wD:9.12,1.0,(13.39,-.93,;12.07,-1.7,;10.74,-.95,;9.41,-1.73,;9.43,-3.25,;8.11,-4.03,;8.13,-5.56,;9.48,-6.32,;9.5,-7.87,;8.16,-8.65,;6.81,-7.91,;6.8,-6.35,;8.19,-10.2,;6.84,-11.16,;5.33,-10.47,;5.32,-8.8,;3.98,-11.43,;2.51,-10.66,;2.45,-9.01,;.98,-8.24,;-.43,-9.13,;-.34,-10.79,;1.12,-11.55,;9.54,-10.96,;9.56,-12.51,;10.86,-10.17,;12.19,-10.9,;13.52,-10.13,;14.84,-10.89,;16.25,-10.22,;17.31,-11.34,;16.55,-12.68,;17.04,-14.12,;16.04,-15.27,;14.53,-14.97,;14.04,-13.53,;15.05,-12.38,;10.76,-4.01,;12.08,-3.24,)| | ||
| Structure | 
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