Reaction Details |
| Report a problem with these data |
Target | Melanocortin receptor 4 |
---|
Ligand | BDBM50217760 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_448693 (CHEMBL897839) |
---|
Ki | 6400±n/a nM |
---|
Citation | Mutulis, F; Kreicberga, J; Yahorava, S; Mutule, I; Borisova-Jan, L; Yahorau, A; Muceniece, R; Azena, S; Veiksina, S; Petrovska, R; Wikberg, JE Design and synthesis of a library of tertiary amides: evaluation as mimetics of the melanocortins' active core. Bioorg Med Chem15:5787-810 (2007) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Melanocortin receptor 4 |
---|
Name: | Melanocortin receptor 4 |
Synonyms: | MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R) |
Type: | Enzyme |
Mol. Mass.: | 36949.50 |
Organism: | Homo sapiens (Human) |
Description: | P32245 |
Residue: | 332 |
Sequence: | MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLL
ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVS
GILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGAN
MKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPL
IYALRSQELRKTFKEIICCYPLGGLCDLSSRY
|
|
|
BDBM50217760 |
---|
n/a |
---|
Name | BDBM50217760 |
Synonyms: | CHEMBL393125 | N-(4-aminobutyl)-N-(naphthalen-2-ylmethyl)-1H-indole-3-carboxamide |
Type | Small organic molecule |
Emp. Form. | C24H25N3O |
Mol. Mass. | 371.4748 |
SMILES | NCCCCN(Cc1ccc2ccccc2c1)C(=O)c1c[nH]c2ccccc12 |
Structure |
|