| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
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| Ligand | BDBM50219106 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_445365 (CHEMBL895655) |
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| Ki | 666±n/a nM |
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| Citation |  Grundt, P; Prevatt, KM; Cao, J; Taylor, M; Floresca, CZ; Choi, JK; Jenkins, BG; Luedtke, RR; Newman, AH Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. J Med Chem50:4135-46 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1A |
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| Name: | 5-hydroxytryptamine receptor 1A |
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| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A |
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| Type: | n/a |
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| Mol. Mass.: | 46122.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 422 |
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| Sequence: | MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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| BDBM50219106 |
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| n/a |
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| Name | BDBM50219106 |
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| Synonyms: | 4-(2,3-dichlorophenyl)-1-(4-(4-(pyridin-2-yl)benzamido)-transbut-2-enyl)piperazine 1-oxide | CHEMBL244775 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H26Cl2N4O2 |
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| Mol. Mass. | 497.416 |
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| SMILES | [O-][N+]1(C\C=C\CNC(=O)c2ccc(cc2)-c2ccccn2)CCN(CC1)c1cccc(Cl)c1Cl |
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| Structure | 
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