| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-dependent kinase 6 |
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| Ligand | BDBM59087 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_526701 (CHEMBL970975) |
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| IC50 | 3400±n/a nM |
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| Citation |  McArdle, BM; Campitelli, MR; Quinn, RJ A common protein fold topology shared by flavonoid biosynthetic enzymes and therapeutic targets. J Nat Prod69:14-7 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Cyclin-dependent kinase 6 |
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| Name: | Cyclin-dependent kinase 6 |
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| Synonyms: | CDK6 | CDK6_HUMAN | CDKN6 | Cell division protein kinase 6 | Cyclin-dependent kinase 6 (CDK 6) | Serine/threonine-protein kinase PLSTIRE |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 36937.42 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q00534 |
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| Residue: | 326 |
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| Sequence: | MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF
QDLERCKENLDSHLPPSQNTSELNTA
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| BDBM59087 |
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| n/a |
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| Name | BDBM59087 |
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| Synonyms: | CHEMBL258765 | Fasca-plysi | Fascaplysin |
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| Type | Small organic molecule |
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| Emp. Form. | C18H11N2O |
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| Mol. Mass. | 271.2922 |
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| SMILES | O=C1c2ccccc2-[n+]2ccc3c([nH]c4ccccc34)c12 |
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| Structure | 
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