| Reaction Details |
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 | Report a problem with these data |
| Target | Free fatty acid receptor 1 |
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| Ligand | BDBM22231 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_519599 (CHEMBL943674) |
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| EC50 | 540±n/a nM |
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| Citation |  Bharate, SB; Rodge, A; Joshi, RK; Kaur, J; Srinivasan, S; Kumar, SS; Kulkarni-Almeida, A; Balachandran, S; Balakrishnan, A; Vishwakarma, RA Discovery of diacylphloroglucinols as a new class of GPR40 (FFAR1) agonists. Bioorg Med Chem Lett18:6357-61 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Free fatty acid receptor 1 |
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| Name: | Free fatty acid receptor 1 |
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| Synonyms: | FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 31473.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O14842 |
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| Residue: | 300 |
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| Sequence: | MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLP
LKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRP
CYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAG
PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPY
NASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
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| BDBM22231 |
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| n/a |
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| Name | BDBM22231 |
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| Synonyms: | (9Z,12Z)-octadeca-9,12-dienoic acid | CHEMBL267476 | Linoleic Acid | Linoleic acid (LA) |
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| Type | Unsaturated fatty acid |
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| Emp. Form. | C18H32O2 |
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| Mol. Mass. | 280.4455 |
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| SMILES | CCCCC\C=C/C\C=C/CCCCCCCC(O)=O |
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| Structure | 
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