| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50170139 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_559971 (CHEMBL1014570) |
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| IC50 | >1000±n/a nM |
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| Citation |  Baraldi, PG; Preti, D; Tabrizi, MA; Romagnoli, R; Saponaro, G; Baraldi, S; Botta, M; Bernardini, C; Tafi, A; Tuccinardi, T; Martinelli, A; Varani, K; Borea, PA Structure-activity relationship studies of a new series of imidazo[2,1-f]purinones as potent and selective A(3) adenosine receptor antagonists. Bioorg Med Chem16:10281-94 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50170139 |
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| n/a |
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| Name | BDBM50170139 |
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| Synonyms: | 1-Benzyl-7-isopropyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione | 1-benzyl-7-isopropyl-3-propyl-1H-imidazo[1,2-a]purine-2,4(3H,8H)-dione | CHEMBL188269 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23N5O2 |
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| Mol. Mass. | 365.4289 |
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| SMILES | CCCn1c(=O)n(Cc2ccccc2)c2nc3[nH]c(cn3c2c1=O)C(C)C |
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| Structure | 
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