| Reaction Details |
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 | Report a problem with these data |
| Target | Cholecystokinin receptor type A |
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| Ligand | BDBM50280135 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_50174 |
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| IC50 | 19±n/a nM |
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| Citation |  Flynn, DL; Villamil, CI; Becker, DP; Gullikson, GW; Moummi, C; Yang, DC 1,3,4-trisubstituted pyrrolidinones as scaffolds for construction of peptidomimetic cholecystokinin antagonists Bioorg Med Chem Lett2:1251-1256 (1992) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholecystokinin receptor type A |
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| Name: | Cholecystokinin receptor type A |
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| Synonyms: | CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49676.37 |
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| Organism: | RAT |
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| Description: | Cholecystokinin central 0 RAT::P30551 |
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| Residue: | 444 |
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| Sequence: | MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQI
LLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLK
DFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAAT
WCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVM
VVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQL
SSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAE
KHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEE
DGRTIRALLSRYSYSHMSTSAPPP
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| BDBM50280135 |
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| n/a |
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| Name | BDBM50280135 |
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| Synonyms: | (3S,4S)-4-[(1H-Indole-2-carbonyl)-amino]-5-oxo-1-phenyl-pyrrolidine-3-carboxylic acid | CHEMBL280733 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H17N3O4 |
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| Mol. Mass. | 363.3667 |
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| SMILES | OC(=O)[C@H]1CN(C(=O)[C@H]1NC(=O)c1cc2ccccc2[nH]1)c1ccccc1 |
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| Structure | 
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