| Reaction Details |
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 | Report a problem with these data |
| Target | Protein kinase C delta type |
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| Ligand | BDBM50290424 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_160778 |
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| IC50 | >500000±n/a nM |
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| Citation |  Zimmermann, J; Buchdunger, E; Mett, H; Meyer, T; Lydon, NB Potent and selective inhibitors of the Abl-kinase: phenylamino-pyrimidine (PAP) derivatives Bioorg Med Chem Lett7:187-192 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein kinase C delta type |
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| Name: | Protein kinase C delta type |
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| Synonyms: | KPCD_HUMAN | PKC delta | PKCD | PRKCD | Protein Kinase C- delta | Protein kinase C, PKC; classical/novel | nPKC-delta |
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| Type: | Enzyme |
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| Mol. Mass.: | 77516.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | The recombinant human PKC enzymes were
produced using a baculovirus expression system in SF9 cells |
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| Residue: | 676 |
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| Sequence: | MAPFLRIAFNSYELGSLQAEDEANQPFCAVKMKEALSTERGKTLVQKKPTMYPEWKSTFD
AHIYEGRVIQIVLMRAAEEPVSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMSVQY
FLEDVDCKQSMRSEDEAKFPTMNRRGAIKQAKIHYIKNHEFIATFFGQPTFCSVCKDFVW
GLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTAANSRDTIFQKERFNIDMPHRFKVHNYMS
PTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCGINQKLLAEALNQVTQRASR
RSDSASSEPVGIYQGFEKKTGVAGEDMQDNSGTYGKIWEGSSKCNINNFIFHKVLGKGSF
GKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKRVLTLAAENPFLTHLICTFQTK
DHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLHSKGIIYRDLKLDNVL
LDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYE
MLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKLFEREPTKRLGVTGNIKIH
PFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQEFLNEKARLSYSDKNLIDSMDQSAF
AGFSFVNPKFEHLLED
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| BDBM50290424 |
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| n/a |
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| Name | BDBM50290424 |
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| Synonyms: | (3-Nitro-phenyl)-(4-pyridin-2-yl-pyrimidin-2-yl)-amine | CHEMBL60816 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H11N5O2 |
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| Mol. Mass. | 293.2801 |
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| SMILES | [O-][N+](=O)c1cccc(Nc2nccc(n2)-c2ccccn2)c1 |
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| Structure | 
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