| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50292473 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_483726 (CHEMBL997481) |
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| IC50 | 10000±n/a nM |
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| Citation |  Cortes, D; Figadere, B; Saez, J; Protais, P Displacement Activity of Bisbenzylisoquinoline Alkaloids at Striatal 3H-SCH 23390 and 3H-Raclopride Binding Sites J Nat Prod55:1281-1286 (1992) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50292473 |
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| n/a |
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| Name | BDBM50292473 |
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| Synonyms: | CHEMBL450155 | CHEMBL506299 | Secantioquine |
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| Type | Small organic molecule |
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| Emp. Form. | C37H38N2O8 |
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| Mol. Mass. | 638.7062 |
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| SMILES | COc1cc2CCN(C)[C@@H](Cc3ccc(OC)c(c3)-c3cc(C=O)ccc3O)c2c(Oc2cc3C(=O)N(C)CCc3cc2OC)c1O |r| |
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| Structure | 
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