| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-dependent kinase 2 |
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| Ligand | BDBM59087 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_582880 (CHEMBL1051861) |
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| IC50 | 500000±n/a nM |
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| Citation |  Aubry, C; Wilson, AJ; Emmerson, D; Murphy, E; Chan, YY; Dickens, MP; García, MD; Jenkins, PR; Mahale, S; Chaudhuri, B Fascaplysin-inspired diindolyls as selective inhibitors of CDK4/cyclin D1. Bioorg Med Chem17:6073-84 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cyclin-dependent kinase 2 |
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| Name: | Cyclin-dependent kinase 2 |
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| Synonyms: | CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 33938.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24941 |
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| Residue: | 298 |
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| Sequence: | MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
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| BDBM59087 |
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| n/a |
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| Name | BDBM59087 |
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| Synonyms: | CHEMBL258765 | Fasca-plysi | Fascaplysin |
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| Type | Small organic molecule |
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| Emp. Form. | C18H11N2O |
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| Mol. Mass. | 271.2922 |
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| SMILES | O=C1c2ccccc2-[n+]2ccc3c([nH]c4ccccc34)c12 |
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| Structure | 
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