| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Transthyretin |
|---|
| Ligand | BDBM50198047 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_599726 (CHEMBL1048170) |
|---|
| IC50 | >50000±n/a nM |
|---|
| Citation |  González, A; Quirante, J; Nieto, J; Almeida, MR; Saraiva, MJ; Planas, A; Arsequell, G; Valencia, G Isatin derivatives, a novel class of transthyretin fibrillogenesis inhibitors. Bioorg Med Chem Lett19:5270-3 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Transthyretin |
|---|
| Name: | Transthyretin |
|---|
| Synonyms: | ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 15884.31 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P02766 |
|---|
| Residue: | 147 |
|---|
| Sequence: | MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS
GPRRYTIAALLSPYSYSTTAVVTNPKE
|
|
|
|---|
| BDBM50198047 |
|---|
| n/a |
|---|
| Name | BDBM50198047 |
|---|
| Synonyms: | (E/Z)-3-(phenylimino)indolin-2-one | 3-(phenylimino)-2-indolinone | 3-(phenylimino)indolin-2-one | CHEMBL227491 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H10N2O |
|---|
| Mol. Mass. | 222.242 |
|---|
| SMILES | O=C1Nc2ccccc2\C1=N\c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
