| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
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| Ligand | BDBM50213235 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_612770 (CHEMBL1071596) |
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| IC50 | 7180±n/a nM |
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| Citation |  Chimenti, F; Fioravanti, R; Bolasco, A; Chimenti, P; Secci, D; Rossi, F; Yáñez, M; Orallo, F; Ortuso, F; Alcaro, S; Cirilli, R; Ferretti, R; Sanna, ML A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors. Bioorg Med Chem18:1273-9 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] B |
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| Name: | Amine oxidase [flavin-containing] B |
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| Synonyms: | AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) |
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| Type: | Protein |
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| Mol. Mass.: | 58768.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P27338 |
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| Residue: | 520 |
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| Sequence: | MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
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| BDBM50213235 |
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| n/a |
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| Name | BDBM50213235 |
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| Synonyms: | (+/-)-7-methoxy-2-(4-methoxyphenyl)chroman-4-one | 7-methoxy-2-(4-methoxyphenyl)chroman-4-one | CHEMBL229908 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H16O4 |
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| Mol. Mass. | 284.3065 |
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| SMILES | COc1ccc(cc1)C1CC(=O)c2ccc(OC)cc2O1 |
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| Structure | 
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